International journal of clinical practice
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Int. J. Clin. Pract. · Jan 2022
Review Meta AnalysisAssociation between Genetic Polymorphisms and Risk of Kidney Posttransplant Diabetes Mellitus: A Systematic Review and Meta-Analysis.
The purpose of this study was to clarify the role of genetic factors on posttransplant diabetes mellitus (PTDM) risk. ⋯ The gene polymorphisms of TCF7L2 rs7903146, KCNQ1 rs2237892, and KCNJ11 rs5219 may predispose kidney transplant recipients to PTDM. Large sample size studies on diverse ethnic populations were warranted to confirm our findings.
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Int. J. Clin. Pract. · Jan 2022
Review Meta AnalysisCan Artificial Intelligence Be Applied to Diagnose Intracerebral Hemorrhage under the Background of the Fourth Industrial Revolution? A Novel Systemic Review and Meta-Analysis.
We intended to provide the clinical evidence that artificial intelligence (AI) could be used to assist doctors in the diagnosis of intracerebral hemorrhage (ICH). ⋯ Under the background of the fourth industrial revolution, AI might be an effective and efficient tool to assist doctors in the clinical diagnosis of ICH.
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Int. J. Clin. Pract. · Jan 2022
Review Meta AnalysisHematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia: An Overview of Systematic Reviews.
Hematopoietic stem cell transplantation (HSCT) has become the main treatment for acute myeloid leukemia (AML) and has been studied in many systematic reviews (SRs), but strong conclusions have not been drawn yet. ⋯ Current SRs show that allo-SCT in the treatment of AML might improve the OS, RFS, and DFS. Auto-SCT has significantly lower TRM but higher RR. Whether bone marrow transplantation is superior to nonmyeloablative chemotherapy remains to be evaluated. Meanwhile, the quality of methodology needs to be further improved. The intensity of evidence was uneven, and the high-quality evidence of outcomes was lacking. Considering the limitations of our overview, more rigorous and scientific studies are needed to fully explore the efficacy of different interventions of HSCT in AML, and clinicians should be more cautious in the treatment.
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Int. J. Clin. Pract. · Jan 2022
Review Meta AnalysisSarcopenia and Mortality Risk of Patients with Sepsis: A Meta-Analysis.
The association between sarcopenia at admission and mortality in patients with sepsis has not been comprehensively evaluated. We performed a meta-analysis to systematically evaluate the above association. ⋯ Current evidence suggests that sarcopenia may be a predictor of mortality in patients with sepsis.
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Int. J. Clin. Pract. · Jan 2022
Review Meta AnalysisDietary Inflammatory Index in relation to Type 2 Diabetes: A Meta-Analysis.
Epidemiologic studies show a strong association between chronic inflammation and type 2 diabetes (T2D). Diet may also affect the risk of T2D by modulating inflammation. This meta-analysis aimed to assess the relation of dietary inflammatory index (DII) and risk of T2D. ⋯ Higher DII might be associated with an increased risk of T2D. Additional well-designed studies are required to confirm this finding.