Neuromodulation : journal of the International Neuromodulation Society
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Spinal cord stimulation (SCS) activates the thalamus, which may be involved in generation of seizures. SCS may therefore influence seizure susceptibility. We investigated the effect of SCS on seizure susceptibility when performed at low frequency (4 Hz) and a frequency in the typical range of SCS treatment (54 Hz). ⋯ Low-frequency SCS is proconvulsive in rats. Further research needs to investigate if this also applies to humans.
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Postherpetic neuralgia (PHN) is the most common complication following an acute varicella zoster virus infection. PHN often results in a chronic severe pain condition refractory to conservative pain management treatments. Peripheral nerve stimulation over the affected spinal nerve root may be an effective treatment option for patients with intractable PHN. ⋯ We describe a case of successful electrode placement at the C2 spinal level for the treatment of refractory PHN.