Neuromodulation : journal of the International Neuromodulation Society
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Ziconotide is an N-type calcium channel (NCC) blocking conopeptide, acting primarily at the NCC-rich dorsal horn. Reported here is an early experience with intrathecal ziconotide in a 55-year-old man with chronic pain resulting from failed back surgery. ⋯ The dosing regimen, onset and resolution of adverse events, and improvement on the primary efficacy measure, the Visual Analog Scale of Pain Intensity, are discussed. Overall, the patient responded positively to ziconotide.
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Objective. The aim of this study was to examine the hypothesis that subcutaneous occipital stimulation influences pain due to occipital neuralgia. Materials and Methods. Between 2001 and 2004 eight patients with intractable occipital neuralgia were referred to our center. Their records were reviewed. ⋯ The total quantity of opiates taken after implantation showed a marked reduction. Of the seven who had a permanent implant two acquired full-time employment. Conclusion. Occipital neuralgia is a useful and reversible treatment for intractable occipital neuralgia.