Neuromodulation : journal of the International Neuromodulation Society
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Electrical signals can be recorded using long-term implanted nerve cuff electrodes in human peripheral nerves. Reliable detection of sensory nerve signals is essential if such signals are to be of use in sensory-based functional electrical stimulation neural prosthetics as a replacement for artificial sensors (switches, strain gauges, etc.). In this review, the signal characteristics of the sensors, the nerve interface, signal processing, and an example of human application to restore motor functions are described.
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Objective. This study examines, in a retrospective fashion, the effects of intraspinal infusion therapy, primarily using opioids, in the treatment of recalcitrant noncancer pain in a sample of 29 consecutive patients. Patients were, on average, 58 years of age having had one surgery, with a pain duration of 221 months. ⋯ Side effects remain fairly common and require continued attention. Their presence, however, did not appear to deter from the patient's overall sense of satisfaction. Acquiring information from significant others and clinic staff may be a useful adjunct in interpreting the overall outcome.