Neuromodulation : journal of the International Neuromodulation Society
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Introduction. At the present time, there is no reliable method or drug for effective relief of the severe pain caused by the amyloldotic polyneuropathy (AP). Objective. ⋯ The patient had the IT treatment for 867 days, of which 777 days (> 90%) were spent at home. Conclusion. Long-term IT administration of opioid and bupivacaine provided satisfactory long-term pain relief in a patient with refractory pain due to AP.
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Introduction. Spinal cord stimulation voltage thresholds have been observed to change with body position, but previously have not been characterized in detail. Design. ⋯ Ninety-five percent of patients experienced an increase, primarily between 11 and 25%. Conclusions. These observations have implications for the design, implantation, and clinical application of spinal cord stimulators.
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Objective and Importance. The subarachnoid infusion of narcotics by programmable devices in patients with chronic non-malignant pain can be a useful therapeutic method. However, certain side-effects, opioid tolerance or changes in the nature of the pain can lead to failure of the therapy. ⋯ The patient therefore needed alternative infusions of both drugs with changes of infusional parameters. Conclusion. The possibility of varying the infusion method of mixed drugs or alternating the drugs is fundamental for successful therapy since neuropathic pain must be considered a dynamic state.