Bulletin of experimental biology and medicine
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Bull. Exp. Biol. Med. · Nov 2013
Effects of erythrocyte microvesicles on the coagulation process stages.
We studied the effect of erythrocyte microvesicles on various stages of platelet-free autoplasma coagulation process. The erythrocyte microvesicles not only exhibited procoagulant activity, but also produced a pronounced anticoagulant effect by inhibiting fibrin formation process. The effects of microvesicles isolated from erythrocytes after 24- and 48-hour cell storage on plasma coagulation were different. The hemocoagulation effects of the "light" and "heavy" microvesicles were studied.