Journal of clinical monitoring and computing
-
Heart rate variability (HRV) is a non-invasive method to measure cardiac autonomic function. Impairments in HRV have been proposed as independent risk factor for increased cardiac mortality and morbidity. Cardio protective phenomenon in females has been hypothesized to be due to differential autonomic tone. ⋯ Sympathetic tone predominates and vagal tone diminishes with aging process. Females showed greater vagal tone than male. This differential autonomic tone indicate age, gender related predisposition to cardiovascular disease.
-
J Clin Monit Comput · Jun 2013
Near real-time notification of gaps in cuff blood pressure recordings for improved patient monitoring.
Blood pressure monitoring during anesthesia is an American Society of Anesthesiology standard. However, the anesthesia provider sometimes fails to engage the patient monitor to make periodic (generally every 3-5 min) measurements of Non-Invasive Blood Pressure (NIBP), which can lead to extended periods (>5 min) when blood pressure is not monitored. We describe a system to automatically detect such gaps in NIBP measurement and notify clinicians in real-time to initiate measurement. ⋯ The maximum gap encountered before SAM was 64 min, while it was 27 min with SAM notification. Real-time notification using SAM is an effective way to reduce both the number of instances and the duration of inadvertent, extended (>15 min) gaps in blood pressure measurements in the operating room. However, the frequency of gaps <15 min could not be reduced using the current configuration of SAM.
-
J Clin Monit Comput · Jun 2013
Heart rate variability analysis during central hypovolemia using wavelet transformation.
Detection of hypovolemia prior to overt hemodynamic decompensation remains an elusive goal in the treatment of critically injured patients in both civilian and combat settings. Monitoring of heart rate variability has been advocated as a potential means to monitor the rapid changes in the physiological state of hemorrhaging patients, with the most popular methods involving calculation of the R-R interval signal's power spectral density (PSD) or use of fractal dimensions (FD). However, the latter method poses technical challenges, while the former is best suited to stationary signals rather than the non-stationary R-R interval. ⋯ Results demonstrate that the proposed DWT-based model outperforms individual PSD and FD methods as well as the combination of these two traditional methods at both sample rates of 500 Hz (p value <0.0001) and 125 Hz (p value <0.0001) in detecting the degree of hypovolemia. These findings indicate the potential of the proposed DWT approach in monitoring the physiological changes caused by hemorrhage. The speed and relatively low computational costs in deriving these features may make it particularly suited for implementation in portable devices for remote monitoring.
-
J Clin Monit Comput · Jun 2013
Clinical refinement of the automatic lung parameter estimator (ALPE).
The automatic lung parameter estimator (ALPE) method was developed in 2002 for bedside estimation of pulmonary gas exchange using step changes in inspired oxygen fraction (FIO₂). Since then a number of studies have been conducted indicating the potential for clinical application and necessitating systems evolution to match clinical application. This paper describes and evaluates the evolution of the ALPE method from a research implementation (ALPE1) to two commercial implementations (ALPE2 and ALPE3). ⋯ Also for ALPE2, the automated FIO2 selection method was successfully applied in 287 patient cases, taking 7.2 ± 2.4 min and was shown to be safe with only one patient having SpO₂ < 86 % when the clinician disabled the alarms. The ALPE method has evolved into two practical, usable systems targeted at clinical application, namely ALPE2 for spontaneously breathing patients and ALPE3 for mechanically ventilated patients. These systems may promote the exploration of the use of more detailed descriptions of pulmonary gas exchange in clinical practice.
-
J Clin Monit Comput · Jun 2013
Comparative Study Observational StudyCardiac output monitoring in septic shock: evaluation of the third-generation Flotrac-Vigileo.
Continuous cardiac index (CI) monitoring is frequently used in critically ill patients. Few studies have compared the pulse contour-based device FloTrac/Vigileo to pulmonary artery thermodilution (PAC) in terms of accuracy for CI monitoring in septic shock. The aim of our study was to compare the third-generation FloTrac/Vigileo to PAC in septic shock. ⋯ The overall correlation coefficient between PAC-CI and FloTrac/Vigileo CI was 0.47 (p < 0.01), with r(2) = 0.22. The area under the curve of the ROC curve for detecting concordant and significant changes in CI was 0.72 (0.53; 0.87). In our study, third-generation Flowtrac-Vigileo appears to be too inaccurate to be recommended for CI monitoring in septic shock.