Journal of clinical monitoring and computing
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J Clin Monit Comput · Jun 2022
Intraoperative impaired cerebrovascular autoregulation and delayed neurocognitive recovery after major oncologic surgery: a secondary analysis of pooled data.
Cerebral blood flow is tightly regulated by cerebrovascular autoregulation (CVA), and intraoperative impairment of CVA has been linked with perioperative neurocognitive disorders. We aim to assess whether impairment of CVA during major oncologic surgery is associated with delayed neurocognitive recovery (DNCR) postoperatively. We performed a secondary analysis of prospectively collected data. ⋯ Intraoperative impairment of CVA is associated with postoperative neurocognitive function early after oncologic surgery. Therefore, intraoperative monitoring of CVA may be a target for neuroprotective interventions. The initial studies were retrospectively registered with primary clinical trial registries recognized by the World Health Organization (ClinicalTrials.gov Identifiers: DRKS00010014, 21.03.2016 and NCT04101006, 24.07.2019).
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J Clin Monit Comput · Jun 2022
Clinical TrialIncongruous effect of phenylephrine on changes in cerebral blood volume measured by near-infrared spectroscopy (NIRS) indicating extracranial contamination.
We assessed extracranial contamination of the near-infrared spectroscopy (NIRS) signal during administration of phenylephrine. The study was performed with NIRO 200NX which employs both the Modified Beer-Lambert (MBL) method to measure total hemoglobin (tHb, expressed in µM), and Spatially Resolved Spectroscopy (SRS) to measure total hemoglobin content (nTHI, expressed in arbitrary units (a.u.)). SRS tends to not be affected by extracranial blood flow. ⋯ The median difference between the Z-scores of nTHI and tHb was - 0.02 [95%CI - 0.04 to - 0.003] (p = 0.03), with a higher variability in the Z-scores of tHb. Phenylephrine induced significant larger changes in MBL values compared to SRS values, indicating that the MBL method might be more prone to extracranial contamination. Trial and clinical registry: Trial registration number: B670201939459, ethical committee number: 2019/0265, date of approval: March 19, 2019.
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J Clin Monit Comput · Jun 2022
Efficacy of evoked potential monitoring for predicting postoperative motor status in internal carotid artery aneurysm surgeries.
This study aimed to investigate the efficacy of intraoperative motor evoked potential (MEP) and somatosensory evoked potential (SSEP) monitoring for predicting postoperative motor deficits (PMDs) in patients with internal carotid artery (ICA) aneurysms. The data for 138 patients with ICA aneurysms who underwent surgical clipping as well as their intraoperative neuromonitoring data were retrospectively reviewed. The efficacy of MEP/SSEP changes for predicting PMDs was assessed using binary logistic regression analysis. ⋯ For SSEP, the value was 14.5 min (p = 0.042, AUC = 0.875). The MEP/SSEP changes adjusted by those optimal values were also identified as independent predictors for short-term (p < 0.001 and p = 0.005, respectively) and long-term PMDs (p = 0.019 and 0.003, respectively). Intraoperative MEP and SSEP deterioration durations are effective in predicting PMDs in patients with ICA aneurysms.
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J Clin Monit Comput · Jun 2022
The impact of video games on training: can it change the game of endotracheal intubation?
In recent years, several studies have demonstrated that the experience derived from video games improves interventions that require technical skills. Airway management is crucial to anesthesiologists, requiring technical and non-technical skills. We evaluated the benefits of video games for video stylet-guided tracheal intubation, which allows the use of video technology in airway management of residents with anesthesiology training. ⋯ Time to intubate the trachea by using video stylet in (Group 1) was found to be 29 s on average, and it was 59.9 s for Group 2 ( p < 0.01) The average number of tracheal intubation attempts was 1.1 in Group 1, and 1.4 in Group 2 (p = 0.19). Video gaming experience improves the visual attention. Those accustomed to playing with video games, video stylet- guided tracheal intubation, performed intubation in less time.
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J Clin Monit Comput · Jun 2022
Machine learning applied to a Cardiac Surgery Recovery Unit and to a Coronary Care Unit for mortality prediction.
Most established severity-of-illness systems used for prediction of intensive care unit (ICU) mortality were developed targeted at the general ICU population, based on logistic regression (LR). To date, no dynamic predictive tool for ICU mortality has been developed targeted at the Cardiac Surgery Recovery Unit (CSRU) and Coronary Care Unit (CCU) using machine learning (ML). CSRU and CCU adult patients from the MIMIC-III critical care database were studied. ⋯ The accuracy statistics less sensitive to unbalanced cohorts were higher for all the ML models. In conclusion, the predictive power of XGB was excellent, substantially outperforming the conventional systems and LR. The ML models developed in this work offer promising results that could benefit CSRU and CCU.