Journal of clinical monitoring and computing
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J Clin Monit Comput · Oct 2016
Respiratory modulations in the photoplethysmogram (DPOP) as a measure of respiratory effort.
DPOP is a measure of the strength of respiratory modulations present in the pulse oximetry photoplethysmogram (pleth) waveform. It has been proposed as a non-invasive parameter for the prediction of the response to volume expansion in hypovolemic patients. The effect of resistive breathing on the DPOP parameter was studied to determine whether it may have an adjunct use as a measure of respiratory effort. ⋯ Further, a relationship between DPOP and percent modulation of the pleth waveform was observed. A version of the DPOP algorithm that corrects for low perfusion was implemented which resulted in an improved relationship between DPOP and PPV. Although a limited cohort of seven volunteers was used, the results suggest that DPOP may be useful as a respiratory effort parameter, given that the fluid level of the patient is maintained at a constant level over the period of analysis.
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J Clin Monit Comput · Oct 2016
Continuous-wave near-infrared spectroscopy is not related to brain tissue oxygen tension.
Near-infrared spectroscopy (NIRS) has gained acceptance for cerebral monitoring, especially during cardiac surgery, though there are few data showing its validity. We therefore aimed to correlate invasive brain tissue oxygen measurements (PtiO2) with the corresponding NIRS-values (regional oxygen saturation, rSO2). We also studied whether NIRS was able to detect ischemic events, defined as a PtiO2-value of <15 mmHg. ⋯ Continuous-wave-NIRS was unable to reliably detect ischemic cerebral episodes, defined as a PtiO2 value <15 mmHg. Displayed NIRS-values did not correlate with invasively measured PtiO2-values. CW-NIRS should not be used for the detection of cerebral ischemia.
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J Clin Monit Comput · Oct 2016
The use of heart rate variability measures as indicators of autonomic nervous modulation must be careful in patients after orthotopic heart transplantation.
The precise relation between heart rate variability (HRV) and autonomic re-innervation has not been established explicitly in patients after orthotopic heart transplantation (OHT), but can be inferred from the fact that the HRV is reduced immediately after OHT and may increase gradually with time. The aim of this study was to investigate the residual HRV in patients about 1-2 years after OHT, as compared with patients after coronary artery bypass graft (CABG) surgery. Thirteen patients who had received OHT and 14 patients who had received CABG surgery were recruited. ⋯ The slope of the power law relation of HRV became positive in OHT patients, instead of negative in CABG patients. We conclude that patients after OHT have residual HRV which were characterized by severely depressed time and frequency domain HRV, increased HR and nHFP, decreased nVLFP, and positive slope of the power-law relation of HRV. The use of nHFP as the indicator of vagal modulation and the use of nVLFP as the indicator of renin-angiotensin modulation, thermoregulation and vagal withdrawal must be careful in the OHT patients.