Journal of clinical monitoring and computing
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J Clin Monit Comput · Dec 1999
Response time of the Opti-Q continuous cardiac output pulmonary artery catheter in the urgent mode to a step change in cardiac output.
This study was conducted to determine the response time of the Opti-Q continuous cardiac output (CCO) device to a step change in cardiac. ⋯ Continuous cardiac output measurement was as accurate as those made by standard bolus thermodilution. The average response time to acute changes in cardiac output was approximately 1.5 minutes or ten times faster than previously reported systems. Response time is independent of animal mass, shunt volume and the direction of cardiac output perturbations.
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J Clin Monit Comput · Dec 1999
Comparative Study Clinical TrialA comparison of pulse oximetry and near infrared spectroscopy (NIRS) in the detection of hypoxaemia occurring with pauses in nasal airflow in neonates.
The aim of this study was to compare the ability of NIRS and pulse oximetry to detect changes in cerebral oxygenation occurring in response to a pause in nasal airflow (PNA). ⋯ We conclude that both techniques are sensitive to changes in oxygenation during PNA. Small changes in cerebral Hbdiff and arterial SpO2 do not always correlate for physiological reasons. A change in Hbdiff of >0.3 micromol 100 g brain(-1) is likely to be physiologically significant and is associated with a change in SpO2 of 12%.
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J Clin Monit Comput · Dec 1999
Clinical TrialValidation of the Natus CO-Stat End Tidal Breath Analyzer in children and adults.
The performance of a point-of-care, noninvasive end tidal breath carbon monoxide analyzer (CO-Stat End Tidal Breath Analyzer, Natus Medical Inc.) that also reports end tidal carbon dioxide (ETCO2) and respiratory rate (RR), was compared to established, marketed (predicate) devices in children (n = 39) and adults (n = 48) who are normal or at-risk of elevated CO excretion. ⋯ We conclude that in a clinical environment the Natus CO-Stat End Tidal Breath Analyzer performs at least as well as predicate devices for the measurements of ETCOc, ETCO2, and RR.