Kaohsiung J Med Sci
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Kaohsiung J Med Sci · Oct 2008
Case ReportsCytologic diagnosis of primary effusion lymphoma in an HIV-negative patient.
Primary effusion lymphoma (PEL) is an unusual and rare type of non-Hodgkin's lymphoma characterized by lymphomatous effusion of pleural, pericardial or peritoneal cavities without lymphadenopathy or organomegaly. It is associated with human herpes virus-8 (HHV-8) and occurs most often in immunodeficient patients. We present a case of PEL in a 69-year-old male presenting with pleural effusion and ascites. ⋯ Immunohistochemically, the lymphoid cells expressed CD138 and multiple myeloma oncogene 1, were positive for HHV-8, and were monoclonal for immunoglobulin heavy chain gene rearrangement. They were negative for Epstein-Barr virus by in situ hybridization. Unfortunately, the patient died during the first course of chemotherapy with cyclophosphamide, vincristine and prednisone.
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Kaohsiung J Med Sci · Oct 2008
Case ReportsAdrenal schwannoma treated with laparoscopic adrenalectomy: a case report.
Schwannoma of the adrenal gland is extremely rare. Here, we report a 49-year-old patient with an adrenal tumor noted incidentally by abdominal ultrasonography while undergoing regular health examination. Retroperitoneal laparoscopic adrenalectomy was performed and the schwannoma was diagnosed by histologic findings and immunohistochemistry. Five months after surgery, the patient remained well and without evidence of recurrence or metastasis.