Minerva anestesiologica
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Minerva anestesiologica · Jan 1995
Clinical TrialGastric intramucosal pH in trauma patients: an index for organ failure risk?
To assess if low gastric intramucosal pH (pHi), in the first 24 hours from trauma, is an early risk index for organ failure in severe trauma. ⋯ Our data suggest that low pHi during the first 24 hours from trauma seems to be a good predictor for the development of organ failure.
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Minerva anestesiologica · Jan 1995
Clinical Trial Controlled Clinical Trial[The use of dobutamine during the intraoperative period to prevent organ hypoperfusion in non-heart surgery. Administration modality and monitoring].
Dobutamine is strongly recommended in the treatment of critical intensive care patients in order to improve cardiac performance and peripheral perfusion. In non-cardiac surgery there are frequent cases of organ hypoperfusion that could be treated with dobutamine; the drug, however, is not advocated since it is difficult to control without invasive hemodynamic monitoring. This study analyzed the possibilities of using and controlling dobutamine in non-cardiac surgery. ⋯ The treated patients showed significantly higher blood pressure, exhaled CO2 and heart rate values, demonstrating that dobutamine infusion can be piloted on the basis of these monitoring parameters. The treated patients had 4% higher exhaled CO2 levels showing the close correlation between exhaled CO2 and the use of the inotrope. The overall results show that dobutamine is easy to use and readily piloted during anesthesia for non-cardiac surgery.