Minerva anestesiologica
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Minerva anestesiologica · May 1995
Comparative Study Clinical Trial Controlled Clinical Trial[Comparison of 2 modified Fick methods and thermodilution for determining the cardiac output in patients with mechanical ventilation].
To evaluate the effectiveness of two cardiac output measurement methods based on a modified Fick equation, that calculate the O2 consumption (VO2) dividing the CO2 production (VCO2) by a fixed respiratory quotient (RQ). ⋯ The correlation coefficients of the two modified Fick methods with COTD are good, and the mean differences between their results and the gold standard are small, but the low precision of both tested methods demonstrated by the very large limits of agreement, severely reduce the clinical reliability of the measurements. Only for the less than 7 L cardiac outputs the COFra limits of agreement with COTD are narrow enough, and in this range the technique can be useful e.g. revealing a low cardiac output.
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Minerva anestesiologica · Apr 1995
[Assessment of intensive therapy: 4-year experience using the Apache II severity score].
To determine the outcome of critically ill patients and to study the characteristics of the population admitted to the intensive care unit. ⋯ These findings suggest that Apache II score is able to investigate critical ill patients, to stratify patients into disease groups and to quantify correctly the overall risk of death but cannot be used in decision making or to govern admissions in intensive care unit.
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Minerva anestesiologica · Mar 1995
Clinical Trial[Effectiveness and modality of continuous infusion administration of atracurium dibesylate].
One-hundred and five patients with ASA I-II were scheduled for general surgery. Atracurium was the muscle-relaxant of choice. ⋯ The neuromuscolar function was investigated evaluating the amplitude of response to TOF and DBS. This procedure proved to be safe, reliable and easily performed in every operating room.
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Minerva anestesiologica · Jan 1995
Clinical TrialGastric intramucosal pH in trauma patients: an index for organ failure risk?
To assess if low gastric intramucosal pH (pHi), in the first 24 hours from trauma, is an early risk index for organ failure in severe trauma. ⋯ Our data suggest that low pHi during the first 24 hours from trauma seems to be a good predictor for the development of organ failure.
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Minerva anestesiologica · Jan 1995
Clinical Trial Controlled Clinical Trial[The use of dobutamine during the intraoperative period to prevent organ hypoperfusion in non-heart surgery. Administration modality and monitoring].
Dobutamine is strongly recommended in the treatment of critical intensive care patients in order to improve cardiac performance and peripheral perfusion. In non-cardiac surgery there are frequent cases of organ hypoperfusion that could be treated with dobutamine; the drug, however, is not advocated since it is difficult to control without invasive hemodynamic monitoring. This study analyzed the possibilities of using and controlling dobutamine in non-cardiac surgery. ⋯ The treated patients showed significantly higher blood pressure, exhaled CO2 and heart rate values, demonstrating that dobutamine infusion can be piloted on the basis of these monitoring parameters. The treated patients had 4% higher exhaled CO2 levels showing the close correlation between exhaled CO2 and the use of the inotrope. The overall results show that dobutamine is easy to use and readily piloted during anesthesia for non-cardiac surgery.