Se Asian J Trop Med
-
Pre-analytical factors should be known and standardized to obtain reliable laboratory test result. If they could not be standardized they should be recognized. ⋯ It is also important to prevent any infection to the patients, the phlebotomists and the environment. The ideal is to get the right sample for the right test at the right time.
-
Se Asian J Trop Med · Jan 1999
Effects of non-analytical factors on the quality of laboratory results.
The quality of clinical laboratory measurement is comprised of 2 phases, the analytical and non-analytical phases. Nowadays, a well established quality control system has been applied. However, the non-analytical phase is a state of the art that must be paid attention to. ⋯ The turnaround time was also a main issue. Verification of test results was an important process too. Finally, as a good laboratory practice, one must has the strategies to detect and eliminate the non-analytical errors.
-
A lot of attempts have been made to standardise both activated partial thromboplastin time (APTT) and prothrombin time (PT). Only the standardization of PT has been successfully implemented while the standardization of APTT is still underway. The PT test is a common method for monitoring oral anticoagulant therapy. ⋯ ISTH/ICSH proposed a calibration model for APTT standardization. As the problem showed a great similarity to PT standardization, the same model of calibration was applied but no international reference preparation for the APTT is yet available. In 1998. van den Besselaar et al proposed a lyophilized APTT reagent comprising synthetic phospholipids and colloidal silica as a candidate IRP for the APTT.