The Journal of clinical endocrinology and metabolism
The most recent articles from:
January 2006
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J. Clin. Endocrinol. Metab. · Jan 2006
Multicenter StudyPartial surgical removal of growth hormone-secreting pituitary tumors enhances the response to somatostatin analogs in acromegaly.
Surgery is a cornerstone in the treatment of acromegaly, but its efficacy in large, invasive tumors is scant. ⋯ Surgical tumor removal (>75%) enhances the response to SSAs without impairing pituitary function. Our data indicate that surgical debulking has a significant place in the treatment algorithm of acromegaly.