The Journal of clinical endocrinology and metabolism
The most recent articles from:
January 2008
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J. Clin. Endocrinol. Metab. · Jan 2008
Randomized Controlled TrialTestosterone therapy prevents gain in visceral adipose tissue and loss of skeletal muscle in nonobese aging men.
Trials of testosterone therapy in aging men have demonstrated increases in fat-free mass (FFM) and skeletal muscle and decreases in fat mass (FM) but have not reported the impact of baseline body composition. ⋯ Testosterone therapy, relative to placebo, selectively lessened visceral fat accumulation without change in total body FM and increased total body FFM and total body and thigh skeletal muscle mass. Further studies are needed to determine the impact of these body compositional changes on markers of metabolic and cardiovascular risk.