The Journal of clinical endocrinology and metabolism
The most recent articles from:
November 2008
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J. Clin. Endocrinol. Metab. · Nov 2008
Oncolytic vaccinia virotherapy of anaplastic thyroid cancer in vivo.
Anaplastic thyroid carcinoma (ATC) is a fatal disease with a median survival of only 6 months. Novel therapies are needed to improve dismal outcomes. ⋯ GLV-1h68 efficiently infects, expresses transgenes within, and inhibits the growth of ATC in vivo. These promising findings support future clinical trials for patients with ATC.