The Journal of clinical endocrinology and metabolism
The most recent articles from: August 2009
-
J. Clin. Endocrinol. Metab. · Aug 2009
Effects of teriparatide treatment and discontinuation in postmenopausal women and eugonadal men with osteoporosis.
In postmenopausal women, bone mineral density (BMD) declines after teriparatide therapy is stopped. The pattern of BMD loss after teriparatide therapy is stopped in men is less clear. ⋯ Teriparatide appears to increase BMD similarly in postmenopausal women and eugonadal men with osteoporosis. After teriparatide is stopped, the decline in BMD is greater in women than in men. If confirmed in larger cohorts, these findings would suggest that the indication for immediate antiresorptive therapy after teriparatide may not be as urgent in men as in women.