The Journal of clinical endocrinology and metabolism
The most recent articles from: January 2011
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J. Clin. Endocrinol. Metab. · Jan 2011
Elevated corticotropin releasing hormone (CRH) during pregnancy and risk of postpartum depression (PPD).
Perinatal depression has a prevalence of 10% with devastating consequences for mother and baby. The prospective identification of those at risk for postpartum (PPD) or prenatal (PND) depression has led to biomarker searches in pregnancy. There are conflicting reports of associations between midpregnancy placental CRH (pCRH) and PPD or PND. ⋯ Higher midpregnancy pCRH was not associated with an increased risk of PND or PPD.