Aust Fam Physician
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Although tramadol induced neuropsychiatric toxicity, dependence and withdrawal have been extensively reported in chronic pain sufferers, such cases continue to surface in clinical practice. ⋯ Patients and prescribers are reminded of the risk of severe morbidity including seizures associated with tramadol withdrawal. Serotonin syndrome can be precipitated with tramadol use especially in combination with other serotonergic drugs.
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Female patients were significantly more likely to present (8 per 1000 encounters) at upper abdominal encounters than were males (6 per 1000). Female patients were over represented (64.5%) compared with total BEACH (56.8%), as were patients of non-English speaking background and patients aged 25-64 years. Aboriginal and Torres Strait Islander patients were seen marginally more often than average at these encounters. Very young and elderly patients were under represented.