Neuroendocrinol Lett
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Neuroendocrinol Lett · Mar 2009
Case ReportsRepeated occurrence of clozapine-induced myocarditis in a patient with schizoaffective disorder and comorbid Parkinson's disease.
Myocarditis is a rare but life threatening adverse effect of clozapine. Some symptoms of myocarditis--elevated temperature, tachycardia and fatigue--appear commonly during the onset of treatment with clozapine and during the dose titration. ⋯ All symptoms disappeared after the discontinuation of the drug. Early diagnosis, discontinuation of clozapine and supportive therapy of myocarditis lower the risk of a fatal outcome.
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Neuroendocrinol Lett · Mar 2009
Randomized Controlled TrialThe epidural steroids in the prevention of epidural fibrosis: MRI and clinical findings.
Epidural fibrosis (EF) represents a frequent and poorly manageable complication of lumbar disk surgery. ⋯ The application of ES did not prove to be useful in the prevention of Failed Back Surgery Syndrome and epidural scar formation. Postoperative pain was decreased in the steroid treated group during the first postoperative week, but not 12 months postoperatively.