An Sist Sanit Navar
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An Sist Sanit Navar · Sep 2014
[Safety and efficacy of a prothrombin complex concentrate in patients with coagulopathy and hemorrhage].
Prothrombin complex concentrates (PCC) are approved for urgent reversal of vitamin K antagonists (VKA). Recently, PCC have been used in the management of massive bleeding-associated coagulopathy. The present work evaluates safety and efficacy of PCC in a case series of both VKA reversal and massive bleeding. ⋯ CCP are safe and effective for the novel indication of adjuvant treatment in massive bleeding patients, as well as for traditional urgent reversal of VKA.