Resp Care
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Comparative Study
The impact of closed endotracheal suctioning systems on mechanical ventilator performance.
Closed endotracheal suctioning during mechanical ventilation is increasingly used, but its impact on ventilator function has not been fully studied. ⋯ There are large differences between the ventilators evaluated (p < 0.001). Closed suctioning does not cause mechanical ventilator malfunction. Upon removal of the suction catheter, these ventilators resumed their pre-suctioning-procedure gas delivery within 2 breaths, and, during all the tested modes, all the ventilators maintained gas delivery. However, closed suctioning can decrease end-expiratory pressure during suctioning.
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Inhalation is a very old method of drug delivery, and in the 20th century it became a mainstay of respiratory care, known as aerosol therapy. Use of inhaled epinephrine for relief of asthma was reported as early as 1929, in England. An early version of a dry powder inhaler (DPI) was the Aerohalor, used to administer penicillin dust to treat respiratory infections. ⋯ Design and lung-deposition improvement of MDIs, DPIs, and nebulizers are exemplified by the new hydrofluoroalkane-propelled MDI formulation of beclomethasone, the metered-dose liquid-spray Respimat, and the DPI system of the Spiros. Differences among aerosol delivery devices create challenges to patient use and caregiver instruction. Potential improvements in aerosol delivery include better standardization of function and patient use, greater reliability, and reduction of drug loss.
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Comparative Study
A laboratory evaluation of 2 mechanical ventilators in the presence of helium-oxygen mixtures.
Helium-oxygen (heliox) mixtures are being used more frequently with mechanical ventilators. Newer ventilators continue to be developed that have not yet been evaluated for safety and efficacy of heliox delivery. We studied the performance of 2 previously untested ventilators (Servo-i and Inspiration) during heliox administration. ⋯ Both Ventilators cycled consistently with heliox mixtures. In most cases, actual delivered V(T) can be reliably calculated if the F(IO2) and the set V(T) or the measured exhaled V(T) is known. With the Servo-i, at high helium concentrations the exhaled V(T) measurement was unreliable and caused a high-priority alarm condition that couldn't be disabled. A supplemental oxygen analyzer is not necessary with either device for heliox applications.