Resp Care
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Randomized Controlled Trial Multicenter Study Comparative Study
A study of the physiologic responses to a lung recruitment maneuver in acute lung injury and acute respiratory distress syndrome.
To determine the magnitude, duration, and consistency of the effects of lung recruitment maneuvers (RMs) on oxygenation, lung mechanics, and comfort in patients with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). ⋯ These results do not support the addition of scheduled RMs to usual treatment for ALI or ARDS.
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Nemaline myopathy is a rare congenital myopathy that generally presents in childhood. We report a case of a 44-year-old man who presented with severe hypoxic hypercapnic respiratory failure as the initial manifestation of nemaline myopathy. ⋯ There are few reported cases of respiratory failure in patients with adult-onset nemaline myopathy, and the insidious onset in this case is even more unusual. This case highlights the varied presenting features of adult-onset nemaline myopathy and that noninvasive ventilation improves respiratory function.
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Comparative Study
The impact of imposed expiratory resistance in neonatal mechanical ventilation: a laboratory evaluation.
Small endotracheal tubes (ETTs) and neonatal ventilators can impact gas exchange, work of breathing, and lung-mechanics measurements in infants, by increasing the expiratory resistance (R(E)) to gas flow. ⋯ The major cause of R(E) appears to be the ventilator exhalation valve. Neonatal ventilators that use a set constant flow during inhalation and exhalation appear to have less R(E) than ventilators that use a variable bias flow during exhalation. Clinical studies are needed to determine whether the imposed R(E) of these ventilator designs impacts gas exchange, lung mechanics, or ventilator weaning.
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Comparative Study
Nail polish does not significantly affect pulse oximetry measurements in mildly hypoxic subjects.
The effect of nail polish on pulse oximetry measurements in non-hypoxic subjects has been studied extensively. Some studies found that nail polish decreased pulse-oximetry (S(pO(2))) values, whereas others found no effects from nail polish. ⋯ With the pulse oximeters and oximetry probes we tested, nail-polish had no significant effect on S(pO(2)) in mildly hypoxic healthy subjects.