Arch Neurol Chicago
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Arch Neurol Chicago · Apr 2004
Randomized Controlled Trial Multicenter Study Clinical TrialTopiramate in migraine prevention: results of a large controlled trial.
Open-label trials and small controlled studies report topiramate's efficacy in migraine prevention. ⋯ Topiramate, 100 or 200 mg/d, was effective as a preventive therapy for patients with migraine.
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Arch Neurol Chicago · Apr 2004
Diffusion-weighted magnetic resonance imaging in internal carotid artery dissection.
Acute multiple brain infarction pattern on diffusion-weighted imaging is associated with arterial or cardiac sources of embolism. ⋯ Acute multiple brain infarction pattern with border zone involvement is frequently found in ICA dissection-related strokes. This finding may further support an interaction of hemodynamic and embolic mechanisms as a cause of cerebral ischemia in this condition.
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Arch Neurol Chicago · Apr 2004
Neuropsychological correlates of basal ganglia and medial temporal lobe NAA/Cho reductions in traumatic brain injury.
Proton magnetic resonance spectroscopy can assess neurochemical sequelae in traumatic brain injury. Metabolic abnormalities are present in the acute or subacute period in patients with traumatic brain injury and correlate with outcome on clinical scales. ⋯ Patients with long-term TBI present a regional correlation pattern that may help identify the neurological basis of cognitive sequelae in traumatic brain injury.