Arch Neurol Chicago
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In humans, Menkes disease is the well-recognized neurological disorder due to inherited copper deficiency. Myelopathy due to acquired copper deficiency is not a well-recognized entity in humans, although myelopathy due to copper deficiency is well documented in some animal species. ⋯ Patients presenting with otherwise unexplained myelopathies should have their serum ceruloplasmin level measured.
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Arch Neurol Chicago · May 2004
Historical ArticleThe aura-headache connection in migraine: a historical analysis.
A historical analysis is presented of insights into the pathogenetic mechanisms related to the migraine aura and headache and how the mechanisms connect. In the traditional sequential concept, advanced through the work of Edward Liveing, MD, Harold G. Wolff, MD, and others, the mechanisms are considered causally connected. A noncausal, parallel concept has been proposed as well and is considered in light of the results of recent animal experimental studies.