Arch Neurol Chicago
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Arch Neurol Chicago · Dec 2006
Randomized Controlled TrialFactors associated with the development of motor fluctuations and dyskinesias in Parkinson disease.
Motor fluctuations and dyskinesias can cause disability and reduce quality of life for patients with Parkinson disease (PD). ⋯ Higher cumulative levodopa doses and higher cumulative levodopa equivalent doses (levodopa plus pramipexole) were associated with the earlier occurrence of motor complications. Motor fluctuations and dyskinesias appear to be interrelated because the presence of one is associated with the earlier development of the other.
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Arch Neurol Chicago · Dec 2006
Frequency and predictors of nonconvulsive seizures during continuous electroencephalographic monitoring in critically ill children.
To determine the incidence, predictors, and timing of nonconvulsive seizures (NCSz) during continuous electroencephalographic monitoring (cEEG) in critically ill children. ⋯ Seizures, the majority being NCSz, are common during cEEG in critically ill children (seen in 44% of patients). Half are detected in the first hour of recording, whereas 20% are not detected until after more than 24 hours of recording. Nonconvulsive seizures are associated with periodic lateralized epileptiform discharges and absence of reactivity on cEEG. This study confirms the importance of prolonged cEEG for critically ill children as a means to detect NCSz.