Brain Stimul
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Randomized Controlled Trial
Effect of two weeks of rTMS on brain activity in healthy subjects during an n-back task: a randomized double blind study.
Repetitive transcranial magnetic stimulation (rTMS) has shown significant efficiency in the treatment of several psychiatric disorders. In depressive disorders, the dorsolateral prefrontal cortex (DLPFC) is the main target for rTMS, but the effects of this stimulation on cognitive functions and their neural correlates are not well known. Previous works have established that the left DLPFC is reliably activated during the n-back working memory task. ⋯ These results show that rTMS applied on the left DLPFC had close and remote effects on brain areas involved in working memory.
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Randomized Controlled Trial
Transcranial direct current stimulation ameliorates tactile sensory deficit in multiple sclerosis.
Deficit of tactile sensation in patients with MS is frequent and can be associated with interference with daily life activities. Transcranial direct current stimulation (tDCS) showed to increase tactile discrimination in healthy subjects. ⋯ Our results indicate that a five day course of anodal tDCS is able to ameliorate tactile sensory loss with long-lasting beneficial effects and could thus represent a therapeutic tool for the treatment of tactile sensory deficit in MS patients.