Clin Lab
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Estrogens are responsible for the development of the secondary female gender characteristics. Serum estradiol concentration measurements depend widely on automated immunoassay systems such as the Architect i2000SR, Cobas e601, and UniCel DxI 800. Here, we compare the performance of three automated immunoassay systems and investigate the correlation of serum estradiol levels. ⋯ The Architect i2000SR system had better precision. The three detection systems have good correlation with each other, but there is a large gap between the results of their detection of estradiol.