Clin Lab
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Pulmonary hamartoma is one of the most common benign tumors of the lung, the symptoms are often atypical, so its diagnosis is not so easy. We presented an elderly man with elevated D-dimer combined persistent acupuncture-like chest pain misdiagnosed as pulmonary embolism finally proved as lung hamartoma with secondary lung infection by bronchoscopy biopsy. ⋯ Elevated D-dimer is not a specific index of pulmonary embolism. When a patient's D-dimer rise combined with severe chest pain, the physician should be wary of pulmonary embolism, myocardial infarction, aortic dissection, and other emergencies, and should also take into account serious infections, tumors, and other diseases. Diagnosis needs further related examination. Chest CT scan has guidance function, and when the chest CT scan suggests the occupying lesion, the pathology examination is the key to identify the benign tumor.
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Case Reports
Acute Hemolytic Transfusion Reaction Due to the "Anti-E" Rhesus Antibody in a Patient with Crohn's Disease.
The rhesus (Rh) system is the second most important blood group system after ABO, with highly immunogenic antigens. Although the anti-E Rh antibody has been reported to cause hemolytic disease of the newborn and delayed hemolytic transfusion reactions, acute hemolytic transfusion reactions (AHTR) have been rarely reported. ⋯ Here is an unusual case of an AHTR due to the anti-E Rh antibody after E-positive RBC transfusion in a patient with Crohn's disease. Because anemia is common in patients with Crohn's disease, it is important to determine the cause of the anemia and necessary to examine the Rh phenotype before transfusions because of the high need for transfusion due to any cause. Awareness of this possibility will ensure safe blood transfusion with special care to screen for antibodies and perform Rh phenotyping, thereby minimizing morbidity and preventing potential mortality.
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Comparative Study
Hematological Indices of Pregnant Women at the University of Gondar Referral Hospital, Northwest Ethiopia: a Comparative Cross-Sectional Study.
Pregnancy is a natural physiological variation as a result of hormonal and metabolic changes. Worldwide a large proportion of women are expected to die each year as a result of pregnancy complication related to hematological profile alterations. Therefore, this study is aimed at assessing hematological indices of pregnant in comparison with non-pregnant women. ⋯ This study found a statistically significant difference in the majority of hematological indices between pregnant and non-pregnant women. Trimesters of pregnancy have an influence on some hematological indices. This study provides baseline data for basic hematological indices changes, and it is vital especially in the antenatal care assessment to avoid pregnancy-related adverse outcomes.
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Detection of carcinoembryonic Antigen (CEA) in pleural effusion has good clinical application value in differentiating benign and malignant pleural effusion, but sometimes CEA provides limited help. We report a case of a patient with left lung neoplasms combined with bilateral pleural effusion with increased CEA in the pleural effusion whose thoracoscopy pleural biopsy pathology was negative, mimicking lung carcinoma and ultimately confirmed as pulmonary sarcomatoid carcinoma by CT-guided percutaneous lung biopsy. ⋯ Elevated pleural effusion CEA is not a specific index of lung cancer. CT-guided percutaneous lung biopsy is appropriate for patients presenting with pleural diseases with lung neoplasms, especially when thoracoscopy pleural biopsy result was negative.
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To compare the prediction values of lymphocyte counts, neutrophil to lymphocyte ratio (NLR), and platelet to lymphocyte ratio (PLR) for the severity and the clinical outcomes of acute cerebral infarction (ACI). ⋯ As an inflammatory and immune biomarker, lymphocyte counts demonstrate similar test perfor-mance as NLR and PLR for predicting the severity and 30-day poor outcomes of ACI.