Minerva ginecologica
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Minerva ginecologica · May 1995
Randomized Controlled Trial Clinical Trial Controlled Clinical Trial[Pharmacologic induction of fetal immobilization for prenatal diagnostic-therapeutic procedures].
Neuro-muscular blocking agents are currently administered to the fetus during intrauterine procedures, in order to freeze fetal movements and to avoid traumatic effects. The authors have evaluated three drug regimens (Pancuronium, Vecuronium, Atracurium), both via the intramuscular and the intravascular route of administration to the fetus. ⋯ The authors speculate that immaturity of fetal metabolism can be responsible for the prolonged action of the drug. No side effect related to paralysis have been recorded at birth and after two years follow-up.