Arch Med Sci
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This study was undertaken to examine the expression of miR-575 in thyroid cancer tissues and to explore its therapeutic potential. ⋯ miR-575 may be used as a therapeutic target for thyroid cancer treatment.
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The aim was to observe the effect of Toll-like receptor 4 (TLR4) deficiency on clinical severity and expression of Th1/Th2/Th17-associated cytokines in experimental autoimmune neuritis (EAN). ⋯ Based on these findings, TLR4 may contribute to the pathogenesis of EAN by regulating Th17 cells and the production of Th17-associated factors. However, the exact mechanism remains unclear and more evidence is needed to elucidate its role in EAN.
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Chronic low back pain (CLBP) is a common and disabling health problem. In this study, we aimed to assess the relationship between pain intensity, the components of catastrophizing, depression and disability in patients with chronic low back pain. ⋯ A multidisciplinary approach is needed for patients with CLBP and should include physical, mental and social evaluation in order to offer an optimal treatment.
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This study examines the feasibility of SilverCloud therapy for anxiety and/or depression. Findings may help determine SilverCloud effectiveness based on patients' profiles. ⋯ This SilverCloud study shows feasibility for participants who had moderate to severe anxiety and/or depression due to social, behavioral, or economic reasons.