Bratisl Med J
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Aim of this study is to investigate COVID-19 outcomes in patients with antiphospholipid syndrome (APS). ⋯ Baseline use of hydroxychloroquine, antiaggregants and anticoagulants may be associated with an absence of new thrombotic event (Tab. 2, Ref. 33).
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The overworld health problem, the incurable disease, the global burden on health insurers and society, and above all one of the leading causes of death - all characterize diabetes mellitus, a lifelong chronic disease that affects hundreds of millions of people around the world. The new types of biosensors bring new opportunities in the care of diabetic patients and improve current methods. The practical relevance of the recent findings is expected in medicine in next years. ⋯ The authors summarized the modern possibilities of biosensing, their pros and cons, and their perspectives for the future. The discussion outcome from the current literature (Tab. 4, Fig. 1, Ref. 63).
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The novel coronavirus disease (COVID-19) pandemic has had a profound global impact economically, socially, and in many other areas. As vaccines are developed and introduced, their effect on the disease on both, the global and individual scale is a subject of intense curiosity. This study aimed to evaluate the relationship between risk factors for hospitalization, disease severity, and vaccination status in COVID-19 inpatients in a pandemic hospital. ⋯ The results of our study indicate that age, disease severity, comorbidities, and vaccination status were factors affecting COVID-19 mortality. Our findings support that full vaccination reduces COVID-19 -related mortality rates, disease severity, and length of hospital stay. However, large-scale studies with larger patient populations are needed (Tab. 2, Ref. 22).
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COVID-19 can also cause multi-organ failure or severe pneumonia. Therefore, new biomarkers are being investigated for rapid diagnosis, early treatment and reduced mortality rates. In this study, D-dimer and albumin were looked at from a different perspective. ⋯ Although albumin had the highest sensitivity values in determining mortality or predicting intensive care admission in our study, we think that D-dimer and DAR may be other parameters to be used to predict intensive care admission and in-hospital mortality (Tab. 5, Fig. 2, Ref. 19) Keywords: COVID-19, albumin, D-dimer, mortality, D-dimer/albumin.
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We aimed to disclose the relationship between restless leg syndrome (RLS) and antiparkinsonian treatment, and its effect on quality of life (QoL) in patients with Parkinson's disease (PD). ⋯ RLS is prevalent among PD patients and night-time dopaminergic over-excitation with levodopa plays an important role in its pathogenesis. Since the symptoms of RLS are associated with decreased QoL, early accurate diagnosis and appropriate adjustment of dopaminergic therapy can lead to immediate relief from RLS symptoms and to QoL improvement (Tab. 4, Fig. 1, Ref. 34).