Bratisl Med J
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The aim of the present study was to determine the prognostic value of thrombocytopenia, platelet indices (MPV/PLT and PDW/PLT) in children with septic shock. ⋯ Platelet indices are useful laboratory parameters in septic shock. MPV/PLT and PDW/PLT ratios can be promising reliable markers for 28-day mortality in children with septic shock (Tab. 4, Fig. 1, Ref. 29).
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The health of seniors is usually characterized by polymorbidity. With regard to quoad vitam prognosis, COVID-19 is extremely risky for seniors. The data on polymorbidity in seniors with COVID-19 are scarce. ⋯ The burden of accompanying diseases in seniors with severe COVID-19 is very high. Seniors living in SCF are particularly at risk (Tab. 5, Fig. 8, Ref. 58).
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We report our experience in starting RATS (robotic-assisted thoracic surgery) lobectomy program during COVID-19 pandemic. ⋯ Safe robotic surgery is based not only on improved robotic equipment, but also on good technical skills and medical knowledge. It requires training of the entire operating room team. The learning curve is steep, involving port placement, use of the correct robotic arms, availability of the proper instrumentation, and proper patient positioning (Tab. 2, Ref. 28).
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Observational Study
Characteristics of COPD patients treated with single‑inhaler triple therapy in real-life clinical practice.
Inflammation associated with chronic obstructive pulmonary disease (COPD) causes narrowing of the airways and destruction of the lung parenchyma. The triple therapy (ICS+LABA+LAMA) may improve lung function, patient‑reported outcomes, and exacerbation risk in a specified subset of GOLD group D patients. A better understanding of the factors leading to the single‑inhaler triple therapy (SITT) prescription in real-life scenario is still an unmet need. ⋯ Despite current treatment, the burden of COPD remains significant in GOLD group D patients. The lung function, symptoms burden and exacerbation history are among the most important factors involved in the decision for stepping up to SITT with potential roles of both bronchodilator and anti-inflammatory components (Tab. 2, Fig. 9, Ref. 66).
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The objective of this study was to evaluate the influence of lip sucking on dentofacial development in a pair of 6.5-year-old monozygotic twins. ⋯ Lip sucking can influence the skeletal development of maxilla, the position of upper and lower incisors and the position of mandible. Skeletal development of mandible seems to be unaffected (Tab. 3, Fig. 1, Ref. 26).