Chinese Med J Peking
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Chinese Med J Peking · Sep 2001
Clinical Trial Controlled Clinical TrialEffects of extrinsic positive end-expiratory pressure on cardiopulmonary function in patients with chronic obstructive pulmonary disease.
To choose one optimal extrinsic positive end-expiratory pressure (PEEPe) for ventilated patients with chronic obstructive pulmonary disease (COPD) and to compare two methods for choosing the optimal level of PEEPe. ⋯ Eighty percent of PEEPi, stz was the upper limit of PEEPe. The results of the two methods used to set the level of PEEPe were identical.
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Chinese Med J Peking · Sep 2001
Comparative StudyComputerized tomography pleurography: a new method for detecting minor pleural lesion.
To evaluate the ability of CT pleurography (CTP) in detecting minor pleural lesions in patients with pleural effusion and to assess its value in distinguishing malignant from benign pleural lesions. ⋯ CTP is superior to conventional CT in detecting and for the differential diagnosis benign and malignant pleural lesions.
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Chinese Med J Peking · Aug 2001
Randomized Controlled Trial Clinical TrialEffects of extrinsic positive end-expiratory pressure on work of breathing in patients with chronic obstructive pulmonary disease.
To investigate the effects of extrinsic positive end-expiratory pressure (PEEPe) on work of breathing in patients with chronic obstructive pulmonary disease (COPD) and their corresponding mechanism. ⋯ WOBp decreases gradually as PEEPe is increased. WOBp decreases by narrowing the difference between the alveolus pressure and the central airway pressure at the end of expiration when PEEPe is applied.
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Chinese Med J Peking · Jul 2001
Protective effect of human CD40-Ig fusion protein in a murine model of acute graft-versus-host disease.
To investigate the protective effects of blocking CD40/CD40L interactions with human CD40-Ig fusion protein in a murine graft-versus-host disease model. ⋯ These results demonstrate that CD40/CD40L interactions play an important role in the pathogenesis of graft-versus-host disease and suggest clinical potential for CD40-Ig in the prevention and treatment of human graft-versus-host disease.
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Chinese Med J Peking · Jun 2001
Efficacy of continuous tracheal gas insufflation in spontaneously breathing canine with acute lung injury.
To investigate the effects of continuous tracheal gas insufflation (CTGI) combined with biphasic intermittent positive airway pressure (BIPAP) ventilation on dogs with spontaneous breathing. ⋯ Using BIPAP combined with CTGI does not cause asynchrony between ventilator and spontaneous breathing, but significantly decreases airway pressure with no influence on hemodynamics and oxygenation. Therefore, BIPAP with CTGI may be a useful support technique, especially in cases where the airway pressure should be limited.