Niger J Clin Pract
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Case Reports
Post native uvulo-tonsillectomy hemorrhage as a cause of acquired long QT syndrome in a Nigerian girl: A case report.
Long QT syndrome (LQTS) is a rare disease entity which until recently was not readily recognized as one of the causes of sudden cardiac death in children. It is a syndrome which can be congenital or acquired and is characterized by the prolongation of the QTc interval, the presence of some electrocardiographic abnormalities and other clinical parameters together with suggestive or definitive family history (Schwartz criteria). ⋯ Possible factors implicated as a cause of the prolongation of the QTc include severe anemia and anesthetic drugs with a probability of an underlying genetic cause. This case highlights a rare cause of sudden cardiac death in children in our environment with the attendant difficulties in making a genetic diagnosis due to inadequate laboratory facilities.
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Bone reduction and shelf preparation is a common procedure to establish a new alveolar plane before implant surgery, which might effect the primary stability. ⋯ IT and RFA are not influenced by bone reduction, shelf preparation, or the implant surface. Primary stability is mostly affected by bone density in the immediate load of 4 implants to support a full-arch prosthesis.
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This experimental study was designed to test the hypothesis that ondansetron, a selective 5-HT3 receptor antagonist, would decrease the duration of motor, sensory, and proprioception blockade in a dose-dependent fashion in a bupivacaine-induced sciatic nerve blockade. ⋯ This is the first study showing that perineural ondansetron administration (800 μg dose) reverses the effect of the local anesthetics and shortens the duration of the motor, sensory, and proprioception functions blockade.
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Schistosomiasis is a neglected infectious tropical disease that is second in occurrence only to hookworm infection in sub-Saharan Africa. Presently, chemotherapy is the main method of control and treatment of this disease due to the absence of a vaccine. ⋯ A number of plant-derived compounds, including alkaloids, terpenes and phenolics, have displayed in vitro and in vivo efficacy against Schistosoma species. This review explores how the application of nanotechnology can improve the efficacy of these plant-derived schistosomicidal compounds through the use of nano-enabled drug delivery systems to improve bioavailability.
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The genital system remains one of the most common sites of carcinogenesis in women. Advances in surgery, radiation treatment, and chemotherapy have increased their efficacy and many patients survive for many years after their initial diagnosis. The eye is a rare site of metastasis from gynecological cancer due to its distant location from the genitalia. ⋯ The mean disease-free interval was found at 25.7 months and mean survival time after the eye metastasis was 13.5 months. Refractory disease was identified as the most important risk factor associated with mortality. Because eye metastasis has such a dismal prognosis, all gynecologists who treat oncological patients should be highly suspicious for reported eye complaints.