Niger J Clin Pract
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Amlodipine, calcium channel blocker (CCB), is used in the management of cardiovascular diseases which causes gingival overgrowth (GO). The growth factors may have a role in the pathogenesis of amlodipine-induced GO. ⋯ These preliminary results suggest that TGF-b1 may play a crucial role in the pathogenesis of amlodipine-induced GO.
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The role of monocytes and high-density lipoprotein (HDL) levels in the pathophysiology of cardiovascular disease (CVD) is well known. However, the relationship between monocytes to HDL-cholesterol ratio (MHR) and CVD in chronic obstructive pulmonary disease (COPD) patients has not been investigated previously. We, therefore, aimed to investigate the predictor role of MHR in the development of CVD in subjects with COPD. ⋯ MHR is significantly associated with CVD in COPD patients. Further prospective studies are warranted to elucidate the predictive value of MHR in COPD patients.
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The purpose of this study was to observe the stresses of all-on-four implant designs in an edentulous mandible in the implant, surrounding bone, and monolithic ceramics. ⋯ In bilateral loading, the force applied to anterior implants does not have a significant effect on the bone structure. Stress concentration increases in posterior angled implants and surrounding bone. Moreover, stress concentration increases as the length of the cantilever, the weakest part in all-on-four implants, increases. As posterior implant angulation increases, stress concentration level and localization are affected.
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Randomized Controlled Trial
Comparative efficacy of medical treatment versus surgical sphincterotomy in the treatment of chronic anal fissure.
Anal fissure which is defined as a longitudinal tear in anoderm below the dentate line is one of the most common benign diseases of anorectal area. Severe pain during the defecation and emotional stress that it causes may reduce people's quality of life. ⋯ LIS is still the gold standard for the treatment of chronic anal fissure when the physicians would like to avoid recurrence and obtain the best pain relief.
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It is a well-established fact that hormonal changes significantly influence the consumer behaviors and their purchase intentions. However, attention to the conspicuous buying due to the mood swings, as a result of hormonal changes, during the pregnancy have been largely ignored in the literature. ⋯ Findings revealed that the women purchase preferences shift as pregnancy move from one trimester to another. Women pay more attention to status products during the 2nd trimester as compared to 1st and 3rd trimesters of pregnancy.