Pak J Med Sci
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To assess the efficacy of muscle energy technique (MET) in combination with conventional physical therapy compared to conventional physical therapy alone following mesenchymal stem cell transplantation in knee osteoarthritis (OA) patients. ⋯ Both groups are effective for improving knee pain, and functional limitation in knee osteoarthritis patients. However, MET Group along with conventional therapy showed marked effects on improving knee pain, knee flexion ROM, and functional limitations after mesenchymal stem cell transplantation in knee osteoarthritis patients.
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To explore the effect of comprehensive nursing intervention on nursing outcomes, self-efficacy, and quality of life in elderly patients with chronic heart failure (CHF). ⋯ For elderly patients with CHF, comprehensive nursing intervention may reduce negative emotions, improve sleep quality, self-care ability, and self-efficacy, and enhance patient compliance, quality of life, and heart function.
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To explore the impact of targeted lifestyle interventions on brain function in young and middle-aged patients with hypertension. ⋯ Targeted lifestyle interventions can significantly improve blood pressure control levels and brain function in young and middle-aged patients with hypertension.
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This study aimed "To identify the factors which increase the vulnerability of self-harm behavior among individuals with substance use and factors which buffer that risk". ⋯ Specific familial, social, and personal factors increase the likelihood of self-harm by causing negative self-evaluation, poor coping skills and psychological distress. This vulnerability ends with self-harm, when combined with conducive environmental situations for the risky behavior. However, the risk can be decreased by providing social and emotional support and encouraging positive mental attitudes.
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Scattered white spots (SWS) seen in the duodenum during esophagogastroduodenoscopy are rare lesions. The histopathologic examination of SWS lesions reveals normal duodenal mucosa (ND), chronic nonspecific duodenitis, and intestinal lymphangiectasia (IL). The intestinal epithelium, through its barrier function, is responsible for tightly controlling antigen traffic from the intestinal lumen to the submucosa. Zonulin plays a crucial role in intestinal barrier function. In this study, we aimed to determine whether there is a relationship between zonulin, the most important marker of leaky gut syndrome, and SWS lesions associated with lymphatic stasis and inflammation in the duodenum. ⋯ Patients with identified SWS more frequently exhibit IL and gastric metaplasia. There is no relationship between SWS and serum zonulin levels.