Rev Invest Clin
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Randomized Controlled Trial Comparative Study
[Decrease of folic acid and cognitive alterations in patients with epilepsy treated with phenytoin or carbamazepine, pilot study].
Phenytoin and carbamazepine were the antiepileptic drugs most frequently used in Mexico and throughout the world. Epileptic patients who take these drugs have a variety of collateral effects including the decrease of folates plasmatic level. Low seric folic acid concentration has been associated with a decline in cognitive functions. The administration of a combined treatment with folic acid could ameliorate these difficulties. ⋯ Treatment with folic acid is safe and without side effects, it improved the cognitive function in patients with epilepsy treated with phenytoin and carbamazepine.
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Review Case Reports
[Malignancy prediction in endocrine pancreas neoplasias].
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Mechanical ventilation plays a central role in the critical care setting; but its use is closely related with some life threatening complications as nosocomial pneumonia and low cardiac performance. One of the most severe complications is called ventilator-associated lung injury (VALI) and it includes: Barotrauma, volutrauma, atelectrauma, biotrauma and oxygen-mediated toxic effects and it is related with an inflammatory response secondary to the stretching and recruitment process of alveoli within mechanical ventilation. The use of some protective ventilatory strategies has lowered the mortality rate 10% approximately.
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Abnormal lung mechanics with diminution of pulmonary volumes and airflows is an adverse effect occurring during the immediate postoperative period of the upper-abdomen surgery. ⋯ Our results suggest that age is inversely related to the pulmonary function decline observed one day after laparoscopic cholecystectomy, which might be explained by the increment of the pain threshold or the decrease of postoperative inhibitory reflexes occurring with aging.
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Wardrop's formula to estimate available oxygen has been used to assess non-critically ill pre-term newborn infants (PTNIs) of 28-32 weeks gestational age who may need red blood cell transfusion ( RBCT ). The use of this formula has not been analyzed in critically-ill PTNIs. The objective of this study was to compare available oxygen levels before and after RBCTs in critically-ill PTNIs of 28-36 weeks gestational age, and to assess is potential usefulness. ⋯ Available oxygen is a good parameter to assess the need for RBCTs in critically-ill PTNIs of 28-36 weeks gestational age. Available oxygen values < 8mL/dL may be another parameter to consider as a criterion for RBCT in these patients.