Saudi Med J
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To assess the immunohistochemistry phenotype of cyclooxygenase-2 (COX-2) in breast cancer (BC) and to correlate it with histological and clinical prognostic factors. ⋯ Cyclooxygenase-2 is a valuable marker that could facilitate BC diagnosis and prognosis.
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To investigate the impact and predictors of tympanostomy tube (TT) extrusion. ⋯ More than one-fourth of the patients who underwent TT insertion for OME developed recurrence. Tympanostomy tube extrusion earlier than 12 months was associated with a higher recurrence rate. Small TTs increased the probability of early TT extrusion.
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To compare the bone mineral density and the fracture risks in Saudi women with and without type 2 diabetes mellitus (T2DM). ⋯ In Saudi women with T2DM, unadjusted FRAX underestimated the risk of MOF and HF. Type 2 diabetes mellitus should be included as one of the clinical risk factors for fracture in future versions of the FRAX score.
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To assess the cytological pattern of thyroid lesions in Najran, Saudi Arabia. ⋯ Most of thyroid lesions in Najran were benign, and females were more affected by thyroid lesions than males. However, papillary carcinoma was the 4th most frequent thyroid lesion in females, while it was the 2nd most frequent in males and diagnosed mainly in younger males (21-40 years). Finally, ages 21-60 years were associated with most of the thyroid lesions in both males and females.
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To detect the cotinine and nicotine serum concentrations of female and male C57BL/6J mice after a 4-week exposure to electronic (e)-cigarette vapors using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). ⋯ This study showed that the gender factor might play a crucial role in nicotine metabolism.