Saudi Med J
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To systematically review evidence on the prevalence of the JAK2V617F (JAK2) mutation and polycythemia vera (PV) among all blood donors, focusing on those with elevated hematocrit. Although blood donors are generally healthy, considering a preclinical stage of myeloproliferative neoplasm, especially in those with polycythemia, is crucial. Evidence on managing these donors is limited. ⋯ The prevalence of the JAK2 mutation among blood donors is similar to the general population's but slightly higher among repeat donors with elevated hematocrit. Further research is necessary to establish definitive upper hemoglobin limits for donor deferral.PROSPERO No.: CRD42023456878.
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Thyroid dysfunction directly affects human health and overall well-being; various approaches are available for the treatment of thyroid diseases, including conservative measures and surgical interventions. Despite advancements in conservative treatment, surgery remains the preferred option. Hypoparathyroidism is the primary cause of hospitalization after thyroidectomy, leading to cost-related concerns and a detrimental impact on patients' overall quality of life. ⋯ This article focused on the presentation, risk factors, and management of hypoparathyroidism to increase awareness of the risks associated with certain variables, thereby enhancing our ability to predict the risk of this condition. Furthermore, this review highlighted the surgical techniques that may be utilized to prevent hypoparathyroidism. These considerations can help guide preoperative discussions regarding the benefits and potential risks of thyroidectomy.
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Comparative Study
Comparing tele-pharmacy and standard clinic follow-up for newly initiated warfarin anticoagulation therapy: A retrospective study.
To compare the effectiveness of providing telepharmacy anticoagulation to on-site clinics in achieving optimal outcomes for patients newly starting warfarin. ⋯ This study demonstrates that patients who receive warfarin for the first time at an anticoagulation clinic can use the telepharmacy method without the fear undesirable outcomes. Results of this study support the continued use and expansion of telepharmacy services in Saudi Arabia. However, further research larger sample sizes and multiple centers is needed to confirm these findings.
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Comparative Study
Comparison of pediatric diabetic ketoacidosis in newly diagnosed versus known patients with type 1 diabetes mellitus: A single-center study.
To compare the demographic, clinical, and biochemical characteristics of newly diagnosed versus known patients with type 1 diabetes mellitus (T1DM) presenting with diabetic ketoacidosis (DKA) in a tertiary care center in the Western region of Saudi Arabia. ⋯ The DKA incidence was higher in newly diagnosed patients, particularly in the middle-childhood age group. Economic factors may contribute to disease manifestations, and newly diagnosed patients had longer DKA symptom durations. The higher DKA incidence and severity in newly diagnosed patients, particularly in certain age groups, underscores the importance of increased disease awareness and early diagnosis.
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Comparative Study
Assessing the accuracy and efficiency of Chat GPT-4 Omni (GPT-4o) in biomedical statistics: Comparative study with traditional tools.
To assess the accuracy of ChatGPT-4 Omni (GPT-4o) in biomedical statistics. The recent novel inauguration of Artificial Intelligence ChatGPT-Omni (GPT-4o), has emerged with the potential to analyze sophisticated and extensive data sets, challenging the expertise of statisticians using traditional statistical tools for data analysis. ⋯ ChatGPT-4 Omni scored better over 80% in all 3 statistical datasets in a short period. GPT-4 Omni also produced accurate graphs and charts as commanded however it required explicit commands with clear instructions to avoid errors and omission of results to achieve appropriate results in biomedical data analysis.