Saudi Med J
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Case Reports
Efficacy of denosumab treatment for lung metastasis secondary to proximal humerus chondroblastoma.
Chondroblastoma is a rare benign cartilaginous tumor that accounts for approximately 1% of bone tumors, but it can be associated with lung metastasis in extremely rare cases, leading to a poor prognosis and death. Herein, we report the case of a 19-year-old male patient who presented with an aggressive chondroblastoma of the proximal humerus and bilateral lung metastasis. The patient was treated with wide local resection, partial metastasectomy, and denosumab. Denosumab treatment was effective in controlling metastatic progression and preventing local recurrence.
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To assess the impact of sarcopenia and vitamin D levels on the severity of lower urinary tract symptoms (LUTS). ⋯ Sarcopenia did not significantly impact LUTS severity, but low vitamin D levels were associated with moderate-to-severe LUTS.
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To describe the current real-world treatment landscape, sequence of therapies, and outcomes in patients with prostate cancer (PC). ⋯ This study provides insights into real-world treatment patterns and clinical outcomes in patients with PC. The findings of this study highlight the importance of adhering to treatment standards and making informed clinical decisions.
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To study the prevalence of thyroid disorders (TDs) among the diabetic population in Arar, Saudi Arabia. ⋯ The findings indicate that the adults in Arar, Saudi Arabia, lack some knowledge of TDs and their relationship to diabetes.
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To assess the prevalence of various frontal sinus fractures (FSF) and examine the relationships between these fractures, types of treatments, and potential complications. ⋯ Frontal sinus fractures were mostly required surgical treatment (63.9%) and post-operative complications occurred especially the neurological and ophthalmic. We recommend studies on the association of complications and different types of obliteration materials.