Saudi Med J
-
Observational Study
Differentiating mycosis fungoides lesions from their mimickers clinically and histologically: A single tertiary center retrospective analysis in Saudi Arabia.
To identify the clinical and histological features of MF that can assist in distinguishing MF from MF-mimicking cases. Although mycosis fungoides (MF) is the most common subtype of cutaneous T-cell lymphoma, clinicopathological correlations are required to establish an accurate diagnosis, which are currently lacking. ⋯ Our proposed diagnostic features are statistically valid and, along with those previously reported, can aid in identifying and distinguishing MF cases from MF-mimicking cases.
-
To systematically review evidence on the prevalence of the JAK2V617F (JAK2) mutation and polycythemia vera (PV) among all blood donors, focusing on those with elevated hematocrit. Although blood donors are generally healthy, considering a preclinical stage of myeloproliferative neoplasm, especially in those with polycythemia, is crucial. Evidence on managing these donors is limited. ⋯ The prevalence of the JAK2 mutation among blood donors is similar to the general population's but slightly higher among repeat donors with elevated hematocrit. Further research is necessary to establish definitive upper hemoglobin limits for donor deferral.PROSPERO No.: CRD42023456878.
-
Thyroid dysfunction directly affects human health and overall well-being; various approaches are available for the treatment of thyroid diseases, including conservative measures and surgical interventions. Despite advancements in conservative treatment, surgery remains the preferred option. Hypoparathyroidism is the primary cause of hospitalization after thyroidectomy, leading to cost-related concerns and a detrimental impact on patients' overall quality of life. ⋯ This article focused on the presentation, risk factors, and management of hypoparathyroidism to increase awareness of the risks associated with certain variables, thereby enhancing our ability to predict the risk of this condition. Furthermore, this review highlighted the surgical techniques that may be utilized to prevent hypoparathyroidism. These considerations can help guide preoperative discussions regarding the benefits and potential risks of thyroidectomy.
-
Comparative Study
Assessing the accuracy and efficiency of Chat GPT-4 Omni (GPT-4o) in biomedical statistics: Comparative study with traditional tools.
To assess the accuracy of ChatGPT-4 Omni (GPT-4o) in biomedical statistics. The recent novel inauguration of Artificial Intelligence ChatGPT-Omni (GPT-4o), has emerged with the potential to analyze sophisticated and extensive data sets, challenging the expertise of statisticians using traditional statistical tools for data analysis. ⋯ ChatGPT-4 Omni scored better over 80% in all 3 statistical datasets in a short period. GPT-4 Omni also produced accurate graphs and charts as commanded however it required explicit commands with clear instructions to avoid errors and omission of results to achieve appropriate results in biomedical data analysis.
-
To determine the seroprevalence of Varicella Zoster virus (VZV) immunoglobulin (Ig)G and IgM antibodies among hemodialysis patients (HDP). Additionally, the presence of VZV viral DNA has been investigated for possible reactivation status. ⋯ In conclusion, significantly higher VZV seroprevalence and antibody levels in HDP indicate greater viral exposure than HC. Screening of hemodialysis (HD) to VZV serologically or at the molecular level is most important to avoid the consequences of viral reactivation, especially in those with asymptomatic HDP.