Middle East journal of anaesthesiology
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Middle East J Anaesthesiol · Jun 2004
Randomized Controlled Trial Comparative Study Clinical TrialPost operative analgesia with continuous epidural infusion.
Forty eight ASA I or II patients of either sex between 20-70 years undergoing major upper abdominal surgery were grouped into sixteen each, on complaint of pain. They received an epidural bolus dose, followed by infusion of the assigned drug at 4ml per hour through BARD PCA I pump. Pain assessment, for the first four hours, was hourly, and subsequently at l0th, 16th, 22nd, 28th, 36th and 40th hour by VAS and VRS. ⋯ In all groups sedation ranged from 0-1. There was hypotension in Group I (2/16).urinary retention in Group II (8/9 not catheterised); unilateral sensory impairment and motor weakness in Group I (3/16) and Group III (1/16). This study showed that continuous infusion of low dose morphine with bupivacaine provides better quality post operative analgesia with fewer side effects than bupivacaine or morphine alone.
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Middle East J Anaesthesiol · Jun 2004
Randomized Controlled Trial Clinical TrialComparison of serum cortisol level in open heart surgery--morphine versus sufentanil.
In open-heart surgery, cardiopulmonary bypass (CPB) can cause a rise in the level of stress hormones such as cortisol. Reducing this hormonal response is beneficial in the recovery period. Anesthetic agents and methods used in such operations have different effects on this response. In the present study two agents (morphine and sufentanil) routinely used for the cardiac surgery in Nemazi Hospital were compared regarding their effect on the serum cortisol levels. ⋯ Neither morphine nor sufentanil in the mentioned doses could reduce the endocrine response in the postoperative period, and thus have no preference, in cardiac surgery.
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Middle East J Anaesthesiol · Jun 2004
Randomized Controlled Trial Clinical TrialEffects of sevoflurane, propofol and position changes on respiratory mechanics.
This study was designed to investigate the effects of propofol, sevoflurane and position changes on respiratory mechanics. Forty patients scheduled for thyroid surgery were divided randomly into two groups; those receiving sevoflurane (group S) (n=20), and those receiving TIVA propofol (group P) (n=22). Dynamic compliance (Cdyn), peak inspiratory pressure (PIP), and respiratory resistance (Rr) values were recorded with a VenTrak respiratory monitor (Novometrix Inc. ⋯ In the S group, dynamic compliance measurements showed changes statistically significant in the supine position (52 +/- 6 mL/cmH2O)) when compared to Induction (47 +/- 9 mL/cmH2O) and Thyroid position (47 +/- 6 mL/cmH2O) measurements (p<0.05). When the groups were compared with each other, there was no significant difference whatsoever at all periods (p>0.05). His concluded that sevoflurane, propofol and position changes exhibit similar effects on respiratory mechanics and blood gases at described dose and concentration.
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Middle East J Anaesthesiol · Jun 2004
Randomized Controlled Trial Clinical TrialHydroxyethylstarch 6% preload does not prevent the hypotension following induction with propofol and fentanyl.
To study the effects of volume preload with hydroxyethylstarch 6% (HES) on the changes in arterial blood pressure and heart rate following propofol/fentanyl induction of anesthesia. ⋯ Administration of 6% HES as a preload did not attenuate the decrease in blood pressure following induction of anesthesia with propofol and fentanyl.
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Middle East J Anaesthesiol · Jun 2004
Review Comparative StudyDesflurane vs. sevoflurane--a review.