Aǧrı : Ağrı (Algoloji) Derneği'nin Yayın organıdır = The journal of the Turkish Society of Algology
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Randomized Controlled Trial
[Comparison of efficacy of gabapentin and amitriptyline in the management of peripheral neuropathic pain].
In this single center, double blind and randomized trial gabapentin as a new anticonvulsant was compared in efficacy and safety with amitriptyline which is a classic agent in neuropathic pain treatment. Fourty six patients with neuropathic pain which was burning, stabbing and shooting in quality were allocated to take gabapentin (group GBP) and amitriptyline (group AMI) monotherapy. The assesment variables were burning, stabbing, shooting pain on visual analog scale (VAS; 0: no pain, 10: worst pain imaginable), allodynia as present or not by lightly touching the skin with cotton. ⋯ Both gabapentin and amitriptyline provided effective pain control in peripheral neuropathic pain. Additionally gabapentin was more effective especially in paroxysmal shooting pain than other pain qualities. And also gabapentin was tolerated well.
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Magnetic resonance imaging (MRI) analysis performed on healthy volunteers assessed the effectiveness of brachial plexus block via the lateral sagittal infraclavicular approach to be easy-performed and relatively safe. In this case report, we presented three cases to whom we performed infraclavicular block via the lateral sagittal approach. One of our cases was a high risk patient with osteomyelitis of the elbow joint and the other was a patient who had required surgery for Dupuytren's contracture. ⋯ Twenty minutes after local anesthetic (LA) injection, sufficient surgical anesthesia was achieved. Non of the patients developed vascular puncture, LA toxicity and pneumothorax. In conclusion, LSIB appears to be an easy, a safe and a more acceptable approach for the patient, therefore a good alternative.