Journal of anaesthesiology, clinical pharmacology
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J Anaesthesiol Clin Pharmacol · Jan 2012
Effect of magnesium sulfate with propofol induction of anesthesia on succinylcholine-induced fasciculations and myalgia.
Magnesium sulfate and propofol have been found to be effective against succinylcholine-induced fasciculations and myalgia, respectively, in separate studies. A prospective randomized double blind controlled study was designed to assess the effect of a combination of magnesium sulfate with propofol for induction of anesthesia on succinylcholine-induced fasciculations and myalgia. ⋯ Magnesium sulfate 40 mg/kg intravenously may be used with propofol for induction of anesthesia to control succinylcholine-induced fasciculations and myalgia.
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J Anaesthesiol Clin Pharmacol · Jan 2012
A comparative randomized study of paravertebral block versus wound infiltration of bupivacaine in modified radical mastectomy.
Paravertebral block (PVB) has the potential to offer long-lasting pain relief because it can uniquely eliminate cortical responses to thoracic dermatomal stimulation. Benefits include a reduction in postoperative nausea and vomiting (PONV), prolonged postoperative pain relief, and potential for ambulatory discharge. ⋯ PVB at the end of the surgery results in better postoperative analgesia, lesser incidence of PONV, and better alertness score.
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J Anaesthesiol Clin Pharmacol · Jan 2012
Comparative evaluation of midazolam and butorphanol as oral premedication in pediatric patients.
To compare oral midazolam (0.5 mg/kg) with oral butorphanol (0.2 mg/kg) as a premedication in 60 pediatric patients with regards to sedation, anxiolysis, rescue analgesic requirement, and recovery profile. ⋯ Oral butorphanol is a better premedication than midazolam in children in view of its excellent sedative and analgesic properties. It does not increase side effects significantly.
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J Anaesthesiol Clin Pharmacol · Jan 2012
Advancement of epidural catheter from lumbar to thoracic space in children: Comparison between 18G and 23G catheters.
Lumbar-to-thoracic advancement of epidural catheter is a safe alternative to direct thoracic placement in children. In this prospective randomized study, success rate of advancement of two different types and gauges of catheter from lumbar-to-thoracic space were studied. ⋯ Advancement of epidural catheter from lumbar to thoracic level was successful in only 10-15% cases but satisfactory analgesia could be provided by increasing the infusion rates.