World journal of gastroenterology : WJG
-
World J. Gastroenterol. · Apr 2015
Comparative StudyEstimating steatosis and fibrosis: Comparison of acoustic structure quantification with established techniques.
To compare ultrasound-based acoustic structure quantification (ASQ) with established non-invasive techniques for grading and staging fatty liver disease. ⋯ ASQ parameters correlate with steatosis, but not with fibrosis in fatty liver disease. Steatosis estimation with ASQ should be further evaluated in biopsy-controlled studies.
-
World J. Gastroenterol. · Apr 2015
Review Meta AnalysisHand-sewn vs linearly stapled esophagogastric anastomosis for esophageal cancer: a meta-analysis.
To compare the outcomes of hand-sewn (HS) and linearly stapled (LS) esophagogastric anastomosis for esophageal cancer. ⋯ This meta-analysis indicates that the LS technique contributes to a reduced rate of leakage and stricture compared with the HS method.
-
World J. Gastroenterol. · Apr 2015
Tong Xie Yao Fang relieves irritable bowel syndrome in rats via mechanisms involving regulation of 5-hydroxytryptamine and substance P.
To investigate whether the Chinese medicine Tong Xie Yao Fang (TXYF) improves dysfunction in an irritable bowel syndrome (IBS) rat model. ⋯ TXYF can modulate the activity of the enteric nervous system and alter 5-HT and SP activities, which may contribute to the symptoms of IBS.
-
World J. Gastroenterol. · Apr 2015
Review Meta AnalysisIntegrin antagonists are effective and safe for Crohn's disease: a meta-analysis.
To evaluate the efficacy and safety of integrin antagonists, including natalizumab and vedolizumab, in Crohn's disease (CD). ⋯ The results prove the efficacy and safety of integrin antagonists for CD treatment, although the treatment strategies varied.
-
World J. Gastroenterol. · Apr 2015
ReviewRole of associating liver partition and portal vein ligation for staged hepatectomy in colorectal liver metastases: a review.
Colorectal cancer is the third most common cancer in the Western world. Approximately half of patients will develop liver metastases, which is the most common cause of death. The only potentially curative treatment is surgical resection. ⋯ In this review, it is shown that with ALPPS the resection rate was 97.1% for CRLM and the mortality rate for all diagnoses was 9.6%. The mortality rate was likely lower for patients with CRLM, but some data were lacking in the reports. Due to the novelty of ALPPS, the indications and technique are not yet established but there are arguments for ALPPS in the context of CRLM and a small FLR.