Zhonghua wei zhong bing ji jiu yi xue
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Aug 2014
[The protective effect of valproic acid on myocardium in rats with lethal scald injury and its mechanism].
To investigate the protective effects of valproic acid (VPA) on myocardium in rats following lethal burn injury and its mechanism. ⋯ VPA can attenuate cardiac injury and improve survival in a rodent model of lethal burn injury. These protective effects may be due to its inhibitory effects on histone deacetylase and caspase-3 activation.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Aug 2014
[The clinical application of pulse indicator continuous cardiac output monitoring in early fluid resuscitation for patients with severe acute pancreatitis].
To evaluate the therapeutic effect of early fluid resuscitation under the guidance of pulse indicator continuous cardiac output (PiCCO) on patients with severe acute pancreatitis (SAP). ⋯ The PiCCO device may be a useful adjunct for fluid resuscitation monitoring in patients with SAP within 72 hours. Early fluid resuscitation under the guidance of PiCCO may be helpful in improving tissue perfusion, reducing the application of blood purification, as well as shortening length of ICU stay. This program did not increase the risk of invasive mechanical ventilation, and no obvious change in mortality rate was observed.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Aug 2014
Comparative Study[Ventilator bundle treatment of acute respiratory distress syndrome and its correlation with biomarkers of inflammation].
To observe the levels of blood soluble urokinase plasminogen activator receptor (suPAR), receptor of advanced glycation end products (RAGE), procalcitonin (PCT) and C-reactive protein (CRP), and to investigate the effect of ventilator bundle (VB) on prognosis of patients with acute respiratory distress syndrome (ARDS). ⋯ Blood suPAR, RAGE, PCT and CRP levels were correlated with the severity of ARDS patients. Compliance of VB can affect the prognosis of patients with ARDS. The high compliance of patients can significantly decrease the levels of blood pro-inflammatory markers, shorten the mechanical ventilation time and ICU length of stay, reduce the incidence of VAP, and it showed a positive impact on patients' prognosis.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Aug 2014
[The clinical value of bedside lung ultrasound in the diagnosis of chronic obstructive pulmonary disease and cardiac pulmonary edema].
To study the diagnostic accuracy of bedside lung ultrasound examination in chronic obstructive pulmonary disease (COPD) and cardiac pulmonary edema. ⋯ We conclude that bedside ultrasound is cost-effective, easy for repeated examination, and suitable for differential diagnosis of lung diseases. It might be useful in screening for COPD and cardiac pulmonary edema.