Zhonghua wei zhong bing ji jiu yi xue
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2015
[The impacts of low-dose corticosteroids infusion given in different manners on refractory septic shock patients].
To discuss the influence of different ways of low-dose corticosteroids infusion on hemodynamics, changes in blood glucose level and prognosis in patients with refractory septic shock. ⋯ Compared with slow intravenous infusion, a continuous intravenous supplementation of small amount of hydrocortisone to patients with refractory septic shock could stabilize blood glucose levels and maintain metabolic balance efficiently. However, in both groups there was no significant difference in the efficiency in stabilizing hemodynamics, shortening shock duration, reducing ICU or hospital days and decreasing 28-day mortality.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2015
[The role of peroxisome proliferator-activated receptor-γ/nuclear factor-ΚB transduction pathway on coagulation disorders induced by sepsis].
To determine the role of activated status of peroxisome proliferator-activated receptorγ/nuclear factor-ΚB (PPAR-γ/NF-ΚB ) in coagulation disorders induced by sepsis. ⋯ PPAR-γ agonist ROSI may ameliorate coagulation disorders in septic rats. PPAR-γ/NF-ΚB transduction pathway plays an important role in septic coagulopathy.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2015
[Analysis of correlation between inflammatory parameters and severity of sepsis caused by bacterial bloodstream infection in septic patients].
To discuss the differences of inflammatory parameters such as procalcitonin (PCT), C-reactive protein (CRP), endotoxin, white blood cell (WBC), neutrophil ratio (Neut%) in blood of septic patients caused by bacterial bloodstream infection, and their correlation with the severity of disease. ⋯ The plasma PCT and CRP have the best correlation between inflammatory parameters and severity of disease in bloodstream infective sepsis patients. CRP has the best diagnostic effect in severe sepsis/septic shock patients with bloodstream infection.