Zhonghua wei zhong bing ji jiu yi xue
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2015
[Analysis of correlation between inflammatory parameters and severity of sepsis caused by bacterial bloodstream infection in septic patients].
To discuss the differences of inflammatory parameters such as procalcitonin (PCT), C-reactive protein (CRP), endotoxin, white blood cell (WBC), neutrophil ratio (Neut%) in blood of septic patients caused by bacterial bloodstream infection, and their correlation with the severity of disease. ⋯ The plasma PCT and CRP have the best correlation between inflammatory parameters and severity of disease in bloodstream infective sepsis patients. CRP has the best diagnostic effect in severe sepsis/septic shock patients with bloodstream infection.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2015
Comparative Study[Comparison of simplified acute physiology score III and other scoring systems in prediction of 28-day prognosis in patients with severe sepsis].
To investigate the power of the simplified acute physiology score III (SAPSIII) for prediction of outcome for patients with severe sepsis admitted to the intensive care unit (ICU). ⋯ (1) For patients with severe sepsis who were admitted to ICU, MEDS was superior to APACHEII, SOFA, SAPSII, and SAPSIII scores in predicting prognosis. MEDS≥11 may indicate a higher mortality rate. (2) SAPSIII score has comparable predictive capability with APACHEII, SOFA and SAPSII scores may be recommended for prediction of the prognosis of patients with severe sepsis in ICU. But the SAPSIII score is unsuitable for predicting the prognosis of patients with acute sepsis in ICU options, and it is not superior to that of SAPSIII score in predicting prognosis of patients with sepsis in the emergency ICU than other score systems.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2015
[The impacts of low-dose corticosteroids infusion given in different manners on refractory septic shock patients].
To discuss the influence of different ways of low-dose corticosteroids infusion on hemodynamics, changes in blood glucose level and prognosis in patients with refractory septic shock. ⋯ Compared with slow intravenous infusion, a continuous intravenous supplementation of small amount of hydrocortisone to patients with refractory septic shock could stabilize blood glucose levels and maintain metabolic balance efficiently. However, in both groups there was no significant difference in the efficiency in stabilizing hemodynamics, shortening shock duration, reducing ICU or hospital days and decreasing 28-day mortality.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2015
[Diagnostic value of serum procalcitonin for infection in the immunocompromised critically ill patients with suspected infection].
To evaluate the diagnostic and prognostic value of the serum procalcitonin (PCT) level in the non-acquired immune deficiency syndrome (AIDS) immunocompromised critically ill patients suspected to have infection. ⋯ The serum level of PCT is found to be a reliable marker for the diagnosis of bacterial infection in immunocompromised critical patients, especially in those with hematologic malignancy. Additionally, PCT provides a useful tool for evaluating the severity of infection and the prognosis of critically ill patients.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2015
[A prospective multicenter clinical study of Xuebijing injection in the treatment of sepsis and multiple organ dysfunction syndrome].
To evaluate the clinical efficacy and safety of Xuebijing injection in treatment of sepsis and multiple organ dysfunction syndrome (MODS). ⋯ Xuebijing injection combined with conventional therapy may effectively ameliorate systemic inflammatory response, protect organ function, alleviate the symptoms, improve organ functions, and elevate the clinical cure rate. Adverse events occur occasionally. Xuebijing injection is found to be safe.