Zhonghua wei zhong bing ji jiu yi xue
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Dec 2019
[Usage of oXiris hemofilter for septic shock patients: a single-center experience].
To evaluate the efficacy and safety of oXiris hemofilter for septic shock patients. ⋯ oXiris hemofilter can effectively remove inflammatory mediators in circulation, significantly improve hemodynamic status and severity, and may be considered as a safe and reliable treatment modality for septic shock patients.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Dec 2019
[Analysis of pressure-time and flow-time curve in ventilator].
To better understand the significance of the pressure-time curve and flow-time curve from the perspective of PB840 ventilator working principle. ⋯ It is helpful to analyze the ventilation state, ventilation failure, and the causes of man-machine confrontation with understanding the ventilation principle and the air route map of the ventilator.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Nov 2019
[Minimum quality threshold in preclinical sepsis studies (MQTiPSS): quality threshold for fluid resuscitation and antimicrobial therapy endpoints].
As outlined in the International Guidelines for Management of Sepsis and Septic Shock: 2016, initial fluid resuscitation and administration of antibiotics are key steps in the early management of sepsis and septic shock. However, such clear guidelines do not exist for preclinical sepsis models. To address these shortcomings, the Wiggers-Bernard conference on preclinical sepsis models was held in Vienna in May 2017. ⋯ To remedy this, antimicrobials are recommended for preclinical studies, with choice and dose adjusted to the specific sepsis model and pathogen(s). Ideally, the administration of antimicrobials should closely mimic clinical practice, taking into account the drug's pharmacokinetic profile, alterations in absorption, distribution and clearance, and host factors such as age, weight, and comorbidities. These recommendations and considerations are proposed as "best practices" for animal models of sepsis that should be implemented.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Nov 2019
Meta Analysis[Xuebijing improves clinical prognosis and reduces mortality in patients with acute paraquat poisoning: a Meta-analysis included 1 429 patients].
To explore the therapeutic effect of Xuebijing on patients with acute paraquat poisoning (APP) by using systematic evaluation method. ⋯ Xuebijing injection can reduce the mortality of patients with APP, which may because that it can improve liver and kidney function, reduce inflammation and oxidative stress damage, inhibit pulmonary fibrosis and increase oxygenation level.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Nov 2019
[Prognostic value of Charlson weighted index of comorbidities combined with sequential organ failure assessment score and procalcitonin in patients with sepsis].
To assess the prognostic value of Charlson weighted index of comorbidities (WIC) combined with sequential organ failure assessment (SOFA) score and procalcitonin (PCT) in sepsis patients in intensive care unit (ICU). ⋯ WIC score, SOFA score combined with serum PCT level can improve the accuracy of predicting the 28-day prognosis in patients with sepsis.